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TERRAGASTRO®

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1 Pack

$40.00
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3 Pack

$120.00
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6 Pack

$240.00
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Weight0.027 kg
Dimensions9.47 x 2.46 x 7.03 cm
NPN

80052841

Size

30 Capsules

Directions

Adults and adolescents (12 and over): Take one capsule daily

SKU

83565900306

Recommended Use

Source of probiotics.

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ABOUT TERRAGASTRO®

TERRAGASTRO® is a lactic acid bacteria blend composed of 3 strains:

  • Pediococcus acidilactici CECT 7483
  • Lactobacillus plantarum CECT 7484
  • Lactobacillus plantarum CECT 7485

This blend is a patented probiotic formula that has beneficial properties for maintaining a good gastro-intestinal health status and reducing the prevalence of IBS

What is a Probiotic?

Probiotics are live micro-organisms which when administered in adequate amounts, confer a health benefit on the host.

If you are looking to complement diet and lifestyle measures to support gastrointestinal health, TERRAGASTRO® may be a suitable option for you.

Recommended Use:
Source of probiotics. Could promote favourable gut flora and help support intestinal/gastrointestinal health.

Medicinal Ingredients (per capsule):
Lactobacillus plantarum……….2.7 billion cfu
Pediococcus acidilactici……..…1.3 billion cfu

Cautions:
This product is intended for adults and adolescents 12 years of age or older. Pregnant and breastfeeding women are advised to consult with their healthcare practitioner prior to using this product

Storage:
Store at room temperature

Safety and drug interactions:
Keep out of reach of children. If you are on antibiotics, take at least 2-3 hours before or after your antibiotics. If you have fever, vomiting, bloody diarrhea or severe abdominal pain, consult a health care practitioner prior to use. If symptoms of digestive upset (e.g. diarrhea) occur, worsen, or persist beyond 3 days, discontinue use and consult a health care practitioner. If you have an immune-compromised condition (e.g. AIDS, lymphoma, patients undergoing long-term corticosteroid treatment), do not use this product. Food Supplements should not be used as a substitute for a varied balanced diet and healthy lifestyle. Keep in a fresh dry place.

How Does it Work?

Serotonin is a primary neurotransmitter that regulates gut motility and sensation. Enterochromaffin (EC) cells secrete the neurotransmitter serotonin into the intestinal wall. Serotonin binds to receptors on nerves to modulate motility, secretion and sensation. SERT (Serotonin reuptake transporter) mediates the uptake of serotonin into epithelial cells to inactivate it. The probiotic bacteria in TERRAGASTRO® produce Short Chain Fatty Acids (SCFAs) that stimulate serotonin release and this may improve gut motility and sensation.

The strains in the TERRAGASTRO® formula are highly resistant to the acidic conditions of the gastrointestinal environment which allows them to pass through the GI tract. It’s ability to adhere to the intestinal epithelium (i.e. cell walls) allows the strains to continuously bind and exert their probiotic effects.

The probiotic bacteria improve microbiota balance by inhibiting the growth of pathogenic and non-beneficial GI bacteria.

Manufacturing

TERRAGASTRO®’s formulation incorporates the novel mixture of Lactobacillus plantarum CECT 7484, 7485 and Pediococcus acidilactici CECT 7483. This concept allows the reduction of symptoms relating to Irritable Bowel Diseases including diarrhea and gut mucosa inflammation.

The rationale of this innovative formulation stands in the fact that digestive diseases impose a great socioeconomic burden to the quality of life. There are no effective cures or treatments, and patients suffering from bowel diseases show three times reduced work ethics compared to healthy individuals.

The product is available in freeze-dried form.

Certifications:

  • Products are produced under the EU standards 178/2002 (Basic food requirements incl. traceability) and 852/2004 (Hygiene, HACCP concept)
  • Allergen Free Statement
  • BSE Free Statement
  • Identify Preserved Status Statement
  • Patent protected
Regulatory Status and Quality Control

IP Status

Probiotic formula is protected by patent WO2011/092261 whose publication date is Aug 4th 2011 and priority date is January 28th 2010 (both European and US provisional patents).

Quality Assurance and Control

The production of TERRAGASTRO® is carried out according to current Good Manufacturing Practices (cGMP) regulations.  All raw materials used for this product are all of food grade quality with certificates from the supplier

GASTROINTESTINAL HEALTH AND DIGESTIVE DISEASES

Referred to as gastrointestinal diseases, they are common disorders which affect the esophagus, stomach, small and large intestines, rectum and other accessory organs including the pancreas, liver and gallbladder.

Alterations in the bowel flora and its activities are now believed to be contributing factors to many chronic and degenerative diseases such as IBS, IBD, Rheumatoid Arthritis, etc, which have all been linked to alterations in the intestinal microflora

IRRITABLE BOWEL DISEASE (IBD)

Inflammatory Bowel Diseases (IBD) are characterized by chronic inflammation in the intestines. Examples of IBD include Ulcerative colitis (UC), Crohn’s Disease and Pouchitis. IBDs can be diagnosed at all ages, but they are most common in young adults, and may consequently induce stunted growth and delayed development. The frequency of IBD is similar to the incidence rates of Type 1 diabetes in Europe and the United States. IBD is treated medically by reducing the inflammation and thereby controlling the gastrointestinal symptoms, however, there is currently no medical cures for inflammatory bowel diseases

IRRITABLE BOWEL SYNDROME (IBS)

Irritable Bowel Syndrome (IBS) is characterized by abdominal pain and/or discomfort which is not associated to altered bowel habit or defecation, where symptoms are not explained by structural or biochemical abnormalities. Urgency, bloating and feeling of incomplete bowel movements are also common in IBS. IBS has a substantial impact on morbidity and quality of life beyond abdominal pain and discomfort, as the associated symptoms affect both the individual’s sense of well-being and the ability to function normally.

Sub-types of IBS include:
• Constipation-predominant (IBS-C)
• Diarrhea-predominant (IBS-D)
• Alternating or Mixed (IBS-A)

To determine whether a person is just having temporary digestive distress or if they do have IBS, doctors use a standard called the Rome III criteria to make a confident diagnosis of IBS: “Symptoms must be present for at least six months and have been experienced on at least three days of at least three months. Specifically, symptoms must consist of recurrent abdominal pain or discomfort with two or more of the following:

• Pain is relieved by a bowel movement
• Onset of pain is related to a change in frequency of stool
• Onset of pain is related to a change in the appearance of stool

CLINICAL RESEARCH

A New Combination of Probiotics Improves IBS-Related Quality of Life 

 (Click here to access full article)

The purpose of the trial was to determine the dose-related effects of a novel probiotic combination, on IBS-related quality of life (IBSQoL). A multi-center, randomized, double-blind, placebo-controlled intervention clinical trial with three parallel arms was designed. 84 patients (53 female, 31 male; age range 20-70 years) with IBS and diarrhea according to Rome-III criteria were randomly allocated to receive one capsule a day for 6 weeks containing: a) I.31 high dose (n=28); b) I.31 low dose (n=27); c) placebo (n=29). At baseline, and 3 and 6 weeks on treatment, patients filled the IBSQOL, Visceral Sensitivity Index (VSI) and global symptom relief questionnaires.

The results indicated that the combination of probiotics improves gut-related well-being. No differences could be observed at baseline between the three treatments. There was a statistically significant improvement in IBS-specific quality of life was observed in both probiotic-treated groups compared to the control group. Gut-related anxiety also improved in both probiotic groups compared to the control group. A strong correlation was observed between the improvement in IBS-specific quality of life and the reduction in gut-related anxiety.  

It was concluded that a combination of three different probiotic bacteria was superior to placebo in improving IBS-related quality of life in patients with IBS and diarrhea.

PATIENT RESOURCES

Brochures

TERRAGASTRO® PATIENT BROCHURE

 

Click here to download the TERRAGASTRO® Patient Brochure

 

 

Educational Videos
 

FREQUENTLY ASKED QUESTIONS

GENERAL INFORMATION QUESTIONS

What is TERRAGASTRO®?
TERRAGASTRO® is a probiotic, whose formula incorporates three strains of lactic acid bacteria, which work to improve gastrointestinal wellbeing.  It significantly improves patients with Irritable Bowel Syndrome and reduces diarrhea, and gut mucosal inflammation.

What is Lactobacillus Plantarum?
Lactobacillus plantarum is a gram positive aerotolerant bacterial organism commonly found in many fermented food products as well as anaerobic plant matter. Once in the intestine, these bacteria attach to the intestinal mucosa and colonize the small intestine, which is essential for their probiotic effect.

What benefits can I expect from TERRAGASTRO®?
TERRAGASTRO® is a probiotic product with the ability to achieve a good intestinal functioning and to favour beneficial intestinal bacterial flora.  It significantly reduces diarrhea, and gut mucosa inflammation and has been shown to significantly improve irritable bowel syndrome (IBS).

When do I start to see results?
Improvements generally begin within 2 weeks and increase with continued use.

Has TERRAGASTRO® been clinically tested?
TERRAGASTRO® has been clinically tested and has been shown to improve Irritable Bowel Syndrome by up to 20% with just 42 days of supplementation.

What causes Irritable Bowel Syndrome?
IBS is multi-factorial: abnormal GI motor functions, visceral hypersensitivity, psychosocial factors, autonomic dysfunction and mucosal immune activation leading to microscopic inflammation of the mucosa. (Camilleri and Andresen, 2009; Spiller, 2007).

TAKING TERRAGASTRO® QUESTIONS

What is the Recommended Use?
Source of Probiotics. Could promote favourable gut flora and help support intestinal/gastrointestinal health.

How many tablets do I take in a day?
One capsule per day

Should I take TERRAGASTRO® with food?
TERRAGASTRO® should be taken with food.

Can I take TERRAGASTRO® with my vitamins?
Yes, TERRAGASTRO® does not affect your vitamins. You can take your daily vitamin supplements with TERRAGASTRO®.

Can children take TERRAGASTRO®?
TERRAGASTRO® is suggested for adults and adolescents 12 years of age and older.

INGREDIENT QUESTIONS

What are the Medicinal Ingredients (per capsule)?
Each capsule contains 33mg Lactobacillus plantarum (CECT 7484, 7485) and 33mg Pediococcus acidilactici (CECT 7483) …….. 3 billion Colony Forming Units (CFU)

Does TERRAGASTRO® contain stimulants?
TERRAGASTRO® contains NO stimulants, herbs, yeast, dairy, artificial colours, sugar or preservatives. It is also mild and well tolerated. TERRAGASTRO® has certifications for allergen-free, BSE-free and sucrose-free statements.

HEALTH AND SAFETY QUESTIONS

Are there any known side effects with the use of TERRAGASTRO®?
Probiotics are Generally Recognized As Safe (GRAS) according to FDA.  There is no evidence of any toxic effects of Lactobacillus plantarum (CECT 7527, 7528 and 7529) in clinical trials. The studies performed using this microorganism demonstrate that it is an absolutely safe and effective compound for reducing blood cholesterol levels.

Does TERRAGASTRO® interact with any drugs that I may be taking?
TERRAGASTRO® has no known drug interactions. Consult your doctor or pharmacist before taking TERRAGASTRO®

PURCHASING QUESTIONS

Can I order TERRAGASTRO® online or over the phone?
Yes, TERRAGASTRO® can be purchased clicking the BUY NOW button above or by calling +1 905 286 9111.

Is TERRAGASTRO® available in stores?
No, TERRAGASTRO® is not available in stores. It is available for purchase online or by calling 1-905-5286-9111.

Do I need a prescription to purchase TERRAGASTRO®?
No, TERRAGASTRO® is available as an OTC nutritional supplement.

How much does TERRAGASTRO® Cost?
One box of TERRAGASTRO® (30 capsules) costs $30.00

How do I pay for TERRAGASTRO®?
We accept all major credit cards (Visa, MasterCard) including PayPal

How long would it take for the product to reach me?
Orders will be processed the same day they are received and will be sent through Canada Post. Please allow 3 to 5 business days depending on your location.

Will my personal information remain private after I order TERRAGASTRO®?
Yes, the information you provide to us will remain private and will never be shared. We will not share your email address, phone number or any personal data.